The Association of Openness Personality Trait with Stress-Related Salivary Biomarkers in Burning Mouth Syndrome
| Autor: | Fabrício Tinôco Alvim de Souza, Arthur Kummer, Tânia Mara Pimenta Amaral, Antônio Lúcio Teixeira, Evandro Neves Abdo, Maiza Luiza Vieira Silva, Tarcília Aparecida Silva, Mauro Henrique Nogueira Guimarães de Abreu |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Oncology medicine.medical_specialty Hydrocortisone education Immunology Burning Mouth Syndrome Behavioral neuroscience Endocrinology Internal medicine Nerve Growth Factor medicine Humans Big Five personality traits Saliva Psychiatry Pathological Aged Mini-international neuropsychiatric interview Neuroticism Interleukin-6 Tumor Necrosis Factor-alpha Endocrine and Autonomic Systems Brain-Derived Neurotrophic Factor Middle Aged Burning mouth syndrome Anxiety Disorders Interleukin-10 stomatognathic diseases Cross-Sectional Studies Neurology Female Psychiatric interview medicine.symptom Psychology Biomarkers Stress Psychological Personality Psychopathology |
| Zdroj: | Neuroimmunomodulation. 22:250-255 |
| ISSN: | 1423-0216 1021-7401 |
| DOI: | 10.1159/000367714 |
| Popis: | Background: Burning mouth syndrome (BMS) is a chronic disorder defined as a burning sensation in the oral mucosa without evidence of pathological findings. Its pathophysiology is largely unknown, but psychiatric disorders and personality traits have been implicated. Objective: This study investigated whether there is any association between salivary biomarkers and personality traits in BMS patients. Methods: It was a cross-sectional, controlled study that evaluated 30 individuals with BMS and 32 controls. All subjects were assessed with a structured psychiatric interview (Mini International Neuropsychiatric Interview) and the Big Five inventory. Salivary levels of brain-derived neurotrophic factor (BDNF), neural growth factor, tumor necrosis factor-α, interleukin (IL)-6, IL-10 and cortisol were determined. Results: We found that BMS patients exhibited more traits of neuroticism and lower openness than controls. Openness showed a moderate and negative correlation with cortisol, BDNF and IL-6. Conclusion: Personality traits are associated with salivary biomarkers in BMS. |
| Databáze: | OpenAIRE |
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