Exaggerated blood pressure response during exercise treadmill testing: functional and hemodynamic features, and risk factors
| Autor: | Sandro G de Lima, Maria de Fátima Pessoa Militão de Albuquerque, João Ricardo Mendes de Oliveira, Danyllo Oliveira, José Eriton Gomes da Cunha, Manuela Barbosa Rodrigues de Souza, Odwaldo Barbosae e Silva, Constância Flávia Junqueira Ayres, R. R. Lemos |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Multivariate statistics Adolescent Physiology Angiotensinogen Hemodynamics Blood Pressure Peptidyl-Dipeptidase A Cohort Studies Young Adult INDEL Mutation Risk Factors Internal medicine Internal Medicine medicine Humans Treadmill Young adult Genetic Association Studies Aged Univariate analysis Polymorphism Genetic business.industry Middle Aged Blood pressure Endocrinology Hypertension Exercise Test Cardiology Female Cardiology and Cardiovascular Medicine business Body mass index Cohort study |
| Zdroj: | Hypertension Research. 35:733-738 |
| ISSN: | 1348-4214 0916-9636 |
| Popis: | The factors which contribute to an exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) are not wholly understood. The association between the insertion/deletion polymorphisms of the angiotensin-converting enzyme (ACE) and M235T of the angiotensinogen with EBPR during ETT still remains unstudied. To identify and compare the risk factors for hypertension between normotensive subjects with EBPR and those who exhibit a normal curve of blood pressure (BP) during ETT. In a series of EBPR cases from a historical cohort of normotensive individuals, a univariate analysis was performed to estimate the association of the studied factors with BP behavior during ETT. Additionally, logistic multivariate regression was conducted to analyze the joint effects of the variables. P-values above 0.05 were considered statistically significant. From a total of 10,027 analyzed examinations, only 219 met the criteria employed to define EBPR, which resulted in a prevalence of 12.6%. For the systolic component of the BP, hyperreactive subjects displayed a mean age and body mass index (BMI) significantly higher than the others (P=0.002 and |
| Databáze: | OpenAIRE |
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