Effectiveness of preventive measures for hemato-oncologic patients undergoing stem cell transplantation during a period of hospital construction
| Autor: | Walter Koller, Alexander Blacky, Peter Kalhs, Birgit Willinger, Ojan Assadian, Magda Diab-Elschahawi, Karl J. Aichberger, Jutta Berger |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Epidemiology Observation period Aspergillosis Young Adult Internal medicine medicine Humans Infection control Hospital Design and Construction Intensive care medicine Aged Cross Infection Infection Control Aspergillus biology business.industry Health Policy Public Health Environmental and Occupational Health Outbreak Middle Aged medicine.disease biology.organism_classification Transplantation Infectious Diseases Hematologic Neoplasms Female Stem cell business Stem Cell Transplantation |
| Zdroj: | American Journal of Infection Control. 39:746-751 |
| ISSN: | 0196-6553 |
| DOI: | 10.1016/j.ajic.2011.01.011 |
| Popis: | Background Aspergillus spp are ubiquitous spore-forming fungi. Construction work, renovation, demolition, or excavation activities within a hospital or in surrounding areas increase the risk for aspergillus infection in susceptible patients and are the main cause of nosocomial aspergillus outbreaks. Methods We investigated the efficacy of infection control measures on the frequency of fungal infection among hemato-oncologic patients undergoing stem cell transplantation during excavation and construction work of an adjacent hospital building. Clinical isolates from these patients obtained before and during the excavation and construction period were analyzed. Preventive measures consisted in the implementation of a multibarrier concept to protect these patients from fungal infection. Results There was no record of any clinical isolate of Aspergillus spp in the observation period before the beginning of the groundwork. However, 3 clinically significant isolates of Aspergillus spp were detected in respiratory tract specimen of 2 patients after the beginning of excavation and demolition work, which were found to be community acquired. Conclusion Although our data cannot demonstrate the efficacy of infection control measures during construction work, it can be concluded that excavation work close to immunocompromised patients is safe if a bundle of preventive measures is implemented before groundwork. |
| Databáze: | OpenAIRE |
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