4-N-Aminoacylfortimicins E
| Autor: | Dave Grampovnik, Richard S. Egan, Daniel A. Dunnigan, Paulette Johnson, Paul Kurath, Preston Hill, Ruth S. Stanaszek, William H. Washburn, James E. Leonard, Momir Cirovic, Jerry R. Martin, Jack Tadanier, Alma W. Goldstein |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Pharmacology
Magnetic Resonance Spectroscopy biology Bacteria Chemical Phenomena Metabolite Microorganism Antimicrobial biology.organism_classification Fortimicin B Microbiology Fortimicin A Anti-Bacterial Agents chemistry.chemical_compound Chemistry Aminoglycosides Biochemistry chemistry Drug Discovery Fermentation Micromonospora |
| Zdroj: | The Journal of antibiotics. 32(9) |
| ISSN: | 0021-8820 |
| Popis: | The conversion of fortimicin E, a minor metabolite from the Micromonospora olivoasterospora fermentation which also produces fortimicin A and fortimicin B, to four 4-N-aminoacylfortimicins E was accomplished. The new 4-N-aminoacylfortimicins E showed only weak antimicrobial activity against several Gram-negative and Gram-positive microorganisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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