A new HLA-A Allele, HLA-A*6824, identified in three unrelated individuals*
| Autor: | J Morris, S Davey, Nina Bendukidze, R Goodman, Colin Brown, S. Day, Vaughan Carter, T Key, P.P.J. Dunn |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Arginine Period (gene) Molecular Sequence Data Immunology Population Lysine Genes MHC Class I Human leukocyte antigen Biology Polymorphism Single Nucleotide Biochemistry White People Exon Genetics Humans Immunology and Allergy Allele education Alleles education.field_of_study HLA-A Antigens Exons General Medicine HLA-A Amino Acid Substitution England Haplotypes Female |
| Zdroj: | Tissue Antigens. 65:485-487 |
| ISSN: | 1399-0039 0001-2815 |
| DOI: | 10.1111/j.1399-0039.2005.00399.x |
| Popis: | A novel allele, human leukocyte antigen (HLA)-A*6824, has been identified in three unrelated individuals of northwestern European origin in a period of less than 4 months, implying that this allele may be quite common in this population. HLA-A*6824 differs from A*680102 by a single nucleotide change at position 275 in exon 2, which results in a conservative amino acid substitution from lysine to arginine in the peptide-binding groove at codon 68. |
| Databáze: | OpenAIRE |
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