Is lower limb salvage worthwhile after severe open tibial fractures in a developing country? An analysis of surgical outcomes, quality of life and cost implications

Autor: Ankit Kumar Garg, Arvinth Shivaa Sethuraman, Raja Bhaskara Rajasekaran, Jayaramaraju Dheenadhayalan, Shanmuganathan Rajasekaran, Yogin Patel, Hari Venkatramani, Shanmuganathan Raja Sabapathy, Agraharam Devendra
Rok vydání: 2021
Předmět:
Zdroj: Injury. 52:996-1001
ISSN: 0020-1383
Popis: Open tibial fractures are rare and difficult-to-treat injuries because of the involvement of bony, skin and neuromuscular injury along with co-morbidities. Often, during the management of very severe cases these injuries, the question arises, should we amputate or salvage the limb? This question has been explored previously in civilian and military contexts in the US and UK but remains unstudied in the alternative sociocultural and economic context of the developing world.We studied 78 adult patients with severe open tibial fracture that presented to our institution, a Level 1 trauma center in India, from February 2018 to June 2019. 20 patients underwent above-knee amputation (AKA), 16 underwent below-knee amputation (BKA), and 42 underwent limb salvage. We assessed injury severity using [our institution's] Open Injury Severity Score (GHOISS), which has separate sub-scores for bony injury, skin injury, neuromuscular injury and co-morbidities, and patients were only included with GHOISS13. We assessed functional outcome measures as well as economic costs as primary cost levied by our institution and other secondary costs.Salvage (LEFS: mean=51, SF-12 PCS: mean=48, SF-12 MCS: mean=49) provided better outcomes to BKA (LEFS: mean=39, p=0.005, SF-12 PCS: mean=40, p=0.003, SF-12 MCS: mean=43, p=0.052) and AKA (LEFS: mean=31, p0.001, SF-12 PCS: mean=34, p0.001, SF-12 MCS: mean=43, p=0.043). Primary costs were higher for limb salvage (index: mean=$3100, total: mean=$4400) than both BKA (index: mean=$2500, p=0.012, total: mean=$2600, p0.001) and AKA (index: mean=$2800, p=0.020, total: mean=$3200, p0.001). Secondary costs were higher for limb salvage than both BKA and AKA (p0.001). Patients who underwent salvage were more likely to return to work at 36 months post-injury compared to below-knee amputees (adjusted OR=0.11, p=0.010).Limb salvage results in better functional outcomes compared with amputation at a higher upfront cost but a likely lower lifetime cost. Unlike other literature on the topic, amputation carries a heavy mental and physical toll in India, likely due to sociocultural differences and stigma. Amputation is a difficult decision for patients to accept and results in poorer outcomes; therefore, we believe that limbs should be aggressively salvaged in our developing country.Therapeutic Level II Prospective Cohort Study.
Databáze: OpenAIRE
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