Survival estimates and outcome predictors for shelter cats with feline panleukopenia virus infection
| Autor: | Regina Hofmann-Lehmann, Paola Rocchi, Tommaso Vezzosi, Barbara Contiero, Federico Porporato, Gabriele Gerardi, Hans Lutz, Marian C. Horzinek, Edoardo Auriemma, Eric Zini, Filippo Ferri |
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| Přispěvatelé: | University of Zurich, Porporato, Federico |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty 10253 Department of Small Animals Feline Panleukopenia 040301 veterinary sciences 3400 General Veterinary Physical examination Feline panleukopenia Animal Welfare Disease Outbreaks Cohort Studies 0403 veterinary science 03 medical and health sciences Lethargy chemistry.chemical_compound Risk Factors Internal medicine Animals Medicine Survival analysis Retrospective Studies CATS Leukopenia 630 Agriculture General Veterinary biology medicine.diagnostic_test business.industry Retrospective cohort study 04 agricultural and veterinary sciences Prognosis biology.organism_classification Survival Analysis 030104 developmental biology Italy chemistry Cats 11404 Department of Clinical Diagnostics and Services 570 Life sciences Veterinary (all) Female Feline Panleukopenia Virus medicine.symptom business Maropitant |
| Popis: | OBJECTIVE To determine survival estimates and outcome predictors for shelter cats with feline panleukopenia virus (FPV) infection. DESIGN Retrospective cohort study. ANIMALS 177 shelter cats with FPV infection. PROCEDURES Medical records of cats treated for FPV infection from 2011 through 2013 were reviewed to collect information pertaining to signalment; history; results of physical examination, CBC, serum biochemical analysis, and blood gas analysis; and treatments (antimicrobials, antiparasitics, antivirals, antiemetics, analgesics, crystalloid or colloid solutions, and blood products). Survival time and outcome predictors were determined by means of Kaplan-Meier estimation, logistic regression, and mixed-model ANOVA. RESULTS Median survival time after hospital admission was 3 days; 20.3% (36/177) of cats survived to discharge from the hospital. Risk of nonsurvival was greater in cats with (vs without) signs of lethargy, rectal temperature < 37.9°C (I00.2°F), or low body weight at hospital admission. Lower (vs higher) leukocyte count on days 3,4, and 7 of hospitalization, but not at admission, was associated with nonsurvival. Amoxicillin–clavulanic acid, antiparasitics, and maropitant but not interferon-ω were associated with survival, whereas glucose infusion was associated with nonsurvival. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that FPV infection carried a poor prognosis for shelter cats. Several variables measured at admission or during hospitalization were associated with outcome. Remarkably and contrary to the existing literature, leukopenia at admission had no association with outcome, possibly owing to early prevention of complications. |
| Databáze: | OpenAIRE |
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