Morphological alteration of seminiferous tubules of testes of Wistar rat offspring exposed to alcohol during pregnancy and/or lactation
| Autor: | Bankole Olusiji Oke, JE Onu, J. O. Oyewale, P.C. Ozegbe |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pregnancy Ethanol Adult female Offspring Alcohol pregnancy lactation testes histomorphometry Wistar rats media_common.quotation_subject Fertility Alcohol Biology medicine.disease Body weight Andrology chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine Lactation medicine media_common |
| Zdroj: | International Journal of Biological and Chemical Sciences; Vol 8, No 1 (2014); 1-7 |
| ISSN: | 1991-8631 1997-342X |
| Popis: | This paper presents the effects of alcohol on the morphology of seminiferous tubules of testes of Wistar rat offspring exposed to alcohol during pregnancy and/or lactation. Seventy five adult female Wistar rats divided into 3 groups of 25 each and their offsprings were used. The offspring of group 1 served as control, those of group 2 were exposed to 2 g/kg body weight of 30% ethanol ( v / v ) during pregnancy and lactation (APL) while those of group 3 were exposed to the same dose of ethanol during lactation only (AL). At Day (D) 7, 14, 21, 35 and 49 of postnatal life, 5 male offspring were randomly selected from the three groups and sacrificed. After the sacrifice, the two testes were dissected out and then prepared for routine histological evaluation. The result of the study showed that the seminiferous epithelia of the testes of the alcohol-exposed groups were characterized by few adluminal as well as defoliated germ cells. The result further showed significant reduction (P |
| Databáze: | OpenAIRE |
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