Demographics, treatment and outcomes of atrial fibrillation in a developing country: the population-based TuRkish Atrial Fibrillation (TRAF) cohort

Autor: Bünyamin Yavuz, Naim Ata, Emre Oto, Deniz Katircioglu-Öztürk, Kudret Aytemir, Banu Evranos, Rasim Koselerli, Emre Ertugay, Abdulkadir Burkan, Emrah Ertugay, Christ P Gale, A. John Camm, Ali Oto
Přispěvatelé: Kardiyoloji
Rok vydání: 2016
Předmět:
Male
Turkey
Epidemiology
Turkish
Health care use
Comorbidity
030204 cardiovascular system & hematology
Cohort Studies
Ambulatory care facilities
Health insurance
0302 clinical medicine
Incidence of atrial fibrillation
Risk Factors
Diagnosis
Atrial Fibrillation
Prevalence
Outpatient clinic
030212 general & internal medicine
Practice Patterns
Physicians'

Transient ischemic attack
Aged
80 and over

Ischemic stroke
Follow-up
Incidence (epidemiology)
Population-based cohort
Atrial fibrillation
Middle Aged
Stroke
Survival Rate
Treatment Outcome
Cohort
Cardiology
CHA2DS2Vasc
Female
Cardiology and Cardiovascular Medicine
Developed country
Anti-Arrhythmia Agents
Adult
medicine.medical_specialty
Adolescent
Developing country
Hemorrhage
Pharmacy
Developing countries
03 medical and health sciences
Young Adult
Age Distribution
Fibrinolytic Agents
Thromboembolism
Physicians
Physiology (medical)
Internal medicine
Developed countries
medicine
Humans
Mortality
Sex Distribution
Developing Countries
Demography
Aged
Retrospective Studies
Pharmacies
business.industry
Quality of care
Anticoagulants
medicine.disease
Cardiovascular System & Cardiology
Morbidity
business
Zdroj: Europace
ISSN: 1532-2092
Popis: Aims: Although atrial fibrillation (AF) is increasingly common in developed countries, there is limited information regarding its demographics, co-morbidities, treatments and outcomes in the developing countries. We present the profile of the TuRkish Atrial Fibrillation (TRAF) cohort which provides real-life data about prevalence, incidence, comorbidities, treatment, healthcare utilization and outcomes associated with AF. Methods and results: The TRAF cohort was extracted from MEDULA, a health insurance database linking hospitals, general practitioners, pharmacies and outpatient clinics for almost 100% of the inhabitants of the country. The cohort includes 507 136 individuals with AF between 2008 and 2012 aged >18 years who survived the first 30 days following diagnosis. Of 507 136 subjects, there were 423 109 (83.4%) with non-valvular AF and 84 027 (16.6%) with valvular AF. The prevalence was 0.80% in non-valvular AF and 0.28% in valvular AF; in 2012 the incidence of non-valvular AF (0.17%) was higher than valvular AF (0.04%). All-cause mortality was 19.19% (97 368) and 11.47% (58 161) at 1-year after diagnosis of AF. There were 35 707 (7.04%) ischaemic stroke/TIA/thromboembolism at baseline and 34 871 (6.87%) during follow-up; 11 472 (2.26%) major haemorrhages at baseline and 10 183 (2.01%) during followup, and 44 116 (8.69%) hospitalizations during the follow-up. Conclusion: The TRAF cohort is the first population-based, whole-country cohort of AF epidemiology, quality of care and outcomes. It provides a unique opportunity to study the patterns, causes and impact of treatments on the incidence and outcomes of AF in a developing country. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017.
Databáze: OpenAIRE