Demographics, treatment and outcomes of atrial fibrillation in a developing country: the population-based TuRkish Atrial Fibrillation (TRAF) cohort
Autor: | Bünyamin Yavuz, Naim Ata, Emre Oto, Deniz Katircioglu-Öztürk, Kudret Aytemir, Banu Evranos, Rasim Koselerli, Emre Ertugay, Abdulkadir Burkan, Emrah Ertugay, Christ P Gale, A. John Camm, Ali Oto |
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Přispěvatelé: | Kardiyoloji |
Rok vydání: | 2016 |
Předmět: |
Male
Turkey Epidemiology Turkish Health care use Comorbidity 030204 cardiovascular system & hematology Cohort Studies Ambulatory care facilities Health insurance 0302 clinical medicine Incidence of atrial fibrillation Risk Factors Diagnosis Atrial Fibrillation Prevalence Outpatient clinic 030212 general & internal medicine Practice Patterns Physicians' Transient ischemic attack Aged 80 and over Ischemic stroke Follow-up Incidence (epidemiology) Population-based cohort Atrial fibrillation Middle Aged Stroke Survival Rate Treatment Outcome Cohort Cardiology CHA2DS2Vasc Female Cardiology and Cardiovascular Medicine Developed country Anti-Arrhythmia Agents Adult medicine.medical_specialty Adolescent Developing country Hemorrhage Pharmacy Developing countries 03 medical and health sciences Young Adult Age Distribution Fibrinolytic Agents Thromboembolism Physicians Physiology (medical) Internal medicine Developed countries medicine Humans Mortality Sex Distribution Developing Countries Demography Aged Retrospective Studies Pharmacies business.industry Quality of care Anticoagulants medicine.disease Cardiovascular System & Cardiology Morbidity business |
Zdroj: | Europace |
ISSN: | 1532-2092 |
Popis: | Aims: Although atrial fibrillation (AF) is increasingly common in developed countries, there is limited information regarding its demographics, co-morbidities, treatments and outcomes in the developing countries. We present the profile of the TuRkish Atrial Fibrillation (TRAF) cohort which provides real-life data about prevalence, incidence, comorbidities, treatment, healthcare utilization and outcomes associated with AF. Methods and results: The TRAF cohort was extracted from MEDULA, a health insurance database linking hospitals, general practitioners, pharmacies and outpatient clinics for almost 100% of the inhabitants of the country. The cohort includes 507 136 individuals with AF between 2008 and 2012 aged >18 years who survived the first 30 days following diagnosis. Of 507 136 subjects, there were 423 109 (83.4%) with non-valvular AF and 84 027 (16.6%) with valvular AF. The prevalence was 0.80% in non-valvular AF and 0.28% in valvular AF; in 2012 the incidence of non-valvular AF (0.17%) was higher than valvular AF (0.04%). All-cause mortality was 19.19% (97 368) and 11.47% (58 161) at 1-year after diagnosis of AF. There were 35 707 (7.04%) ischaemic stroke/TIA/thromboembolism at baseline and 34 871 (6.87%) during follow-up; 11 472 (2.26%) major haemorrhages at baseline and 10 183 (2.01%) during followup, and 44 116 (8.69%) hospitalizations during the follow-up. Conclusion: The TRAF cohort is the first population-based, whole-country cohort of AF epidemiology, quality of care and outcomes. It provides a unique opportunity to study the patterns, causes and impact of treatments on the incidence and outcomes of AF in a developing country. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. |
Databáze: | OpenAIRE |
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