Hypereosinophilic syndrome: an indolent rash with a serious cardiac complication
| Autor: | D. Lefroy, S. H. Wakelin, D. Milojkovic, E. E. Merika |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
medicine.medical_specialty Dermatology 030204 cardiovascular system & hematology Asymptomatic Coronary artery disease 03 medical and health sciences 0302 clinical medicine Fibrosis Internal medicine Hypereosinophilic Syndrome medicine Humans Eosinophilia cardiovascular diseases Hypereosinophilic syndrome business.industry Coronary Aneurysm Restrictive cardiomyopathy Disease Management Exanthema medicine.disease Thrombosis Rash Aortic Aneurysm cardiovascular system Cardiology Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Clinical and Experimental Dermatology. 41:170-174 |
| ISSN: | 0307-6938 |
| DOI: | 10.1111/ced.12709 |
| Popis: | Idiopathic hypereosinophilic syndrome (HES) is a rare disorder, characterized by prominent blood or tissue eosinophilia with ensuing tissue damage, which is diagnosed after exclusion of underlying diseases known to cause HES. Sustained eosinophilia is associated with cardiac disease, including endomyocardial thrombosis and fibrosis, leading to restrictive cardiomyopathy, valvular dysfunction and increased thrombotic tendency. Aneurysmal coronary artery disease (CAD) occurring in the absence of stenotic atherosclerotic plaques is extremely rare. We present a case of idiopathic HES in a 30-year-old woman with asymptomatic multianeurysmal CAD and a sinus of Valsalva aneurysm, and discuss a brief review of the literature and management strategies. |
| Databáze: | OpenAIRE |
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