Perfusion and spectroscopy magnetic resonance imaging in a case of lymphocytic vasculitis mimicking brain tumor

Autor: Ferdinando Caranci, Gennaro Esposito, Arturo Di Blasi, Luca Brunese, Carmine Franco Muccio, Felice D'Arco
Přispěvatelé: Muccio, Cf, Di Blasi, A, Esposito, G, Brunese, Luca, D'Arco, F, Caranci, Ferdinando, C. F., Muccio, A., Di Blasi, G., Esposito, L., Brunese, F., D'Arco
Jazyk: angličtina
Rok vydání: 2013
Předmět:
In vivo magnetic resonance spectroscopy
medicine.medical_specialty
magnetic resonance imaging (MRI)
Central nervous system
Brain tumor
Case Report
Neuroimaging
medicine
diffusion weighted imaging
proton magnetic resonance spectroscopy (1H MRS)
primary angiitis of central nervous system (PACNS)
brain tumor diagnostics
proton magnetic resonance spectroscopy (¹H MRS)
diffusion weighted imaging
perfusion weighted imaging
magnetic resonance imaging (MRI)

medicine.diagnostic_test
business.industry
Magnetic resonance imaging
medicine.disease
perfusion weighted imaging
medicine.anatomical_structure
primary angiitis of central nervous system (PACNS)
brain tumor diagnostics
proton magnetic resonance spectroscopy (¹H MRS)
brain tumor diagnostic
Radiology
Differential diagnosis
business
Perfusion
Diffusion MRI
Zdroj: Polish Journal of Radiology
Popis: Summary Background: Lymphocytic vasculitis of the central nervous system is an uncommon subtype of primary angiitis of the central nervous system (PACNS) – a rare inflammatory disorder affecting parenchymal and leptomeningeal arteries and veins. Case Report: Establishing diagnosis on the basis of neuroimaging only is difficult, as it can mimic a brain tumor. Thus, histological diagnosis is essential for appropriate management. We present a case of biopsy-proven lymphocytic vasculitis mimicking a brain tumor on neuroimaging that was subsequently successfully treated with steroid therapy. We also discuss the findings in perfusion MR (PWI) and MR spectroscopy (MRS). Conclusions: Regional hypoperfusion on PWI and elevation of glutamate and glutamine levels on MRS (without associated typical tumor spectra) are common findings in inflammatory disorders, including PACNS, and can be useful in differential diagnosis with tumors.
Databáze: OpenAIRE