Associations between the autonomic nervous system and the second derivative of the finger photoplethysmogram indices
| Autor: | Atsushi Kohjitani, Sachi Ohno, Yoko Iwase, Masaaki Miyata, Kazuna Sugiyama, Akina Tohya, Yozo Manabe, Teruto Hashiguchi |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Aging Adolescent Baroreflex Autonomic Nervous System Young Adult Heart Rate Internal medicine Diabetes mellitus Photoplethysmogram Heart rate Hyperlipidemia Internal Medicine medicine Heart rate variability Humans Photoplethysmography Aged Retrospective Studies Aged 80 and over business.industry Biochemistry (medical) Middle Aged medicine.disease Autonomic nervous system medicine.anatomical_structure Endocrinology Cardiovascular Diseases Vascular resistance Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of atherosclerosis and thrombosis. 21(5) |
| ISSN: | 1880-3873 |
| Popis: | Aim: The indices of the second derivative of the finger photoplethysmogram(SDPTG) denote stiffness of large arteries, peripheral vascular resistance and vascular aging. However, the association between the autonomic nervous activity and the SDPTG indices has not yet been elucidated. Methods: The SDPTG and heart rate variability(HRV) were consecutively measured in the sitting position on the day before surgery in 168 patients 18-89 years of age. The relationships between the SDPTG indices(b/a, c/a, d/a and e/a) and HRV indices(power spectral analysis and time domain analysis parameters) were analyzed. The relationships between c/a and atherosclerosis-based conditions and risk factors for atherosclerosis were also evaluated. Results: The SDPTG index b/a was negatively associated and the d/a index was positively associated with the low-frequency(LF)(R=−0.44 and 0.42, respectively) and high-frequency(HF) components(R=−0.31 and 0.35, respectively). The SDPTG index c/a was also positively associated with the LF(R=0.40) and HF(R=0.44) components. A multivariate regression analysis showed that the LF, HF and heart rate were independent determinants of the c/a. Furthermore, the c/a values were significantly lower in the patients with hypertension, diabetes mellitus and hyperlipidemia than in those without these diseases, and a reduced c/a was significantly associated with increased serum triglyceride and total cholesterol concentrations. Conclusions: These findings suggest that a decrease in c/a is associated with a reduced baroreflex response of the peripheral vasomotor activity and a decreased cardiac parasympathetic activity. Furthermore, a decrease in c/a was found to be associated with atherosclerosis-based conditions, such as hypertension, diabetes mellitus and hyperlipidemia. |
| Databáze: | OpenAIRE |
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