Local-regional and distant recurrence rates in skin-sparing mastectomies compared with non-skin-sparing mastectomies
| Autor: | Barry W. Feig, William Fraser Symmans, E. Singletary, Anthony Lucci, Isabelle Bedrosian, H. M. Kuerer, K. K. Hunt, Steven J. Kronowitz, M. I. Ross, Khazi M. Nayeemuddin, Min Yi, Rosa F. Hwang, Frederick C. Ames, Funda Meric-Bernstam |
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| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | ResearcherID |
| ISSN: | 1538-7445 0008-5472 |
| DOI: | 10.1158/0008-5472.sabcs-4138 |
| Popis: | Abstract #4138 Background: Although skin-sparing mastectomies (SSMs) are becoming more common, there are few data regarding the local-regional and distant recurrence rates. The aim of this study was to examine the incidence of local-regional recurrence, distant recurrence, and survival in breast cancer patients who underwent SSMs or non-skin-sparing mastectomies (NSSMs) at our institution. Methods: We reviewed records of patients with primary breast carcinoma stage 0 to III who underwent total mastectomies with or without complete axillary dissection at our center from January 2000 to December 2005. After excluding patients with bilateral breast cancer, mastectomies for recurrent breast cancer, and patients with less than two-year follow-up, there were 1623 patients for study. Patient and tumor characteristics were evaluated and comparisons undertaken between the SSM and NSSM groups with univariate and multivariate logistic analyses. Kaplan-Meier curves and log-rank test were used to evaluate the overall and disease-free survival in the two groups. RESULTS: Of the 1623 patients, 465 (28.7%) patients underwent SSM and 1158 (71.3%) underwent NSSM. Patients who underwent NSSM were older (55.6 vs. 48.9, p Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 4138. |
| Databáze: | OpenAIRE |
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