Clinical effects of a new mouthrinse containing chlorhexidine, cetylpyridinium chloride and zinc-lactate on oral halitosis

Autor: Silvia Roldán, Edwin Winkel, A.J. van Winkelhoff, David Herrera, Mariano Sanz
Přispěvatelé: Personalized Healthcare Technology (PHT)
Rok vydání: 2003
Předmět:
Male
Mouthwashes
Placebo-controlled study
Dentistry
Cetylpyridinium chloride
law.invention
Placebos
chemistry.chemical_compound
Randomized controlled trial
law
double-blind placebo-controlled study
Aged
80 and over
Chlorhexidine
Parallel study
Middle Aged
VOLATILE SULFUR-COMPOUNDS
Smell
Zinc
Treatment Outcome
Periodontics
SALIVARY-GLAND HYPOFUNCTION
Female
OIL-WATER MOUTHRINSE
zinc-lactate
medicine.drug
Adult
BREATH-ODOR
Cetylpyridinium
FLUID BALANCE
Placebo
Statistics
Nonparametric
mouthrinse
Double-Blind Method
Tongue
cetylpyridinium chloride
MALODOR
medicine
Humans
Gargling
Lactic Acid
volatile sulfur compounds
Aged
Periodontitis
SULFIDE MONITOR
Sulfur Compounds
business.industry
CONSUMPTION
Halitosis
medicine.disease
REDUCTION
chemistry
Anti-Infective Agents
Local
Tooth Discoloration
PERIODONTITIS
business
Follow-Up Studies
Zdroj: Journal of Clinical Periodontology, 30(4), 300-306. Wiley
ISSN: 0303-6979
DOI: 10.1034/j.1600-051x.2003.00342.x
Popis: Objectives: The aim of this double-blind, parallel study was to test the clinical efficacy of a newly developed mouthrinse in the treatment of oral halitosis in patients without periodontitis. Material and methods: Forty volunteers, recruited in two centers, participated in this study. Patients were selected on the basis of (1) halitosis of oral origin, (2) full-mouth organoleptic score >1, using an arbitrary 0-5 scale, (3) level of volatile sulfur compounds (VSC) >170 parts per billion (ppb) and (4) Winkel tongue coating index (WTCI) > 4 (0-12). Intervention included gargling with a mouthrinse containing chlorhexidine (0.05%), cetylpyridinium chloride (0.05%) and zinc-lactate (0.14%) or with a placebo mouthrinse without active ingredients. At days 0 and 14 clinical variables were assessed in order of performance: (1) organoleptic assessments, (2) levels of VSC, and (3) WTCI. Results: Treatment with the active mouthrinse resulted in a significant mean reduction in the organoleptic score from 2.8 to 1.5 (p
Databáze: OpenAIRE
Externí odkaz: