Influence of Acupuncture on the Outcomes of in Vitro Fertilisation When Embryo Implantation Has Failed: A Prospective Randomised Controlled Clinical Trial
| Autor: | Daniela Isoyama Manca di Villahermosa, Mariana Balthazar Nogueira, Caio Parente Barbosa, Lara Guercio dos Santos, Fabia Lima Vilarino |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Acupuncture Therapy Fertilization in Vitro Moxibustion Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Acupuncture medicine Humans Embryo Implantation Prospective Studies 030212 general & internal medicine Dry needling 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Pregnancy Outcome General Medicine medicine.disease Combined Modality Therapy Embryo transfer Surgery Abortion Spontaneous Pregnancy rate Treatment Outcome Complementary and alternative medicine Women's Health Female Ovulation induction Neurology (clinical) business Infertility Female |
| Zdroj: | Acupuncture in Medicine. 31:157-161 |
| ISSN: | 1759-9873 0964-5284 |
| DOI: | 10.1136/acupmed-2012-010269 |
| Popis: | Objective To evaluate the effectiveness of acupuncture and moxibustion as an adjuvant treatment in women undergoing in vitro fertilisation (IVF) when embryo implantation has failed. Methods A prospective, randomised controlled clinical trial was conducted with 84 infertile patients who had had at least two unsuccessful attempts of IVF. The patients were randomised in three groups: control (n=28), sham (n=28) and acupuncture (n=28). The sample size was calculated by assuming a pregnancy rate of 10% when embryo implantation had failed. The pregnancy rates of the current IVF cycle were evaluated by measurement of blood β human chorionic gonadotrophin (βhCG) and subsequent transvaginal ultrasound. Acupuncture was performed on the first and seventh day of ovulation induction, on the day before ovarian puncture and on the day after embryo transfer. In the acupuncture group, patients were treated with moxibustion at nine acupuncture points (BL18, BL22, BL23, BL52, CV3, CV4, CV5, CV7, GV4) and needling at 12 points. In the sham group needles were inserted in eight areas that did not correspond to known acupuncture points. Results The clinical pregnancy rate in the acupuncture group was significantly higher than that in the control and sham groups (35.7% vs 7.1% vs 10.7%; p=0.0169). Conclusions In this study, acupuncture and moxibustion increased pregnancy rates when used as an adjuvant treatment in women undergoing IVF, when embryo implantation had failed. |
| Databáze: | OpenAIRE |
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