Does DNCB therapy potentiate epicutaneous sensitization to non‐related contact allergens?
| Autor: | J.P. Nater, A. C. de Groot, M. C. J. M. de Jong, E. Bleumink |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Alopecia Areata medicine.medical_treatment Dermatology Dermatitis Contact Dithranol Dinitrochlorobenzene medicine Humans Epicutaneous sensitization Contact allergens Child Nitrobenzenes integumentary system business.industry Contact hypersensitivity Immunotherapy Anthralin Middle Aged Alopecia areata medicine.disease medicine.anatomical_structure Scalp Immunology Drug Therapy Combination Female Drug Eruptions business medicine.drug |
| Zdroj: | Clinical and Experimental Dermatology, 6(2), 139-144. Wiley-Blackwell |
| ISSN: | 0307-6938 |
| Popis: | Summary Nineteen patients suffering from alopecia areata were treated weekly with both 2,4-dinitro-chlorobenzene (DNCB) and dithranol applied to separate areas on the scalp. During treatment seven patients developed contact hypersensitivity to dithranol. Our findings indicate that repeated topical application of DNCB may increase the susceptibility of the treated individual to contact allergens. This would constitute a serious draw-back in the acceptibility of DNCB immunotherapy. |
| Databáze: | OpenAIRE |
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