Residential magnetic fields as a risk factor for childhood acute leukaemia: Results from a German population-based case-control study
| Autor: | Joachim Schüz, Jörg Michaelis, Jan-Peter Grigat, Karl Brinkmann |
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| Rok vydání: | 2001 |
| Předmět: |
Male
Cancer Research Pediatrics medicine.medical_specialty Time Factors Adolescent Population German Electromagnetic Fields German population Risk Factors Germany Epidemiology Odds Ratio medicine Humans Risk factor Child education Leukemia Radiation-Induced Childhood Cancer Registry education.field_of_study Leukemia business.industry Infant Newborn Case-control study Infant Dose-Response Relationship Radiation equipment and supplies language.human_language Oncology Case-Control Studies Child Preschool language Population study Female business human activities Demography |
| Zdroj: | International Journal of Cancer. 91:728-735 |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/1097-0215(200002)9999:9999<::aid-ijc1097>3.0.co;2-d |
| Popis: | Our objective was to investigate whether exposure to residential power-frequency (50 Hz) magnetic fields above 0.2 μT increases a child's risk of leukaemia and to confirm or reject a finding from a previous German study on this topic, which reported increased leukaemia risk with exposure to stronger magnetic fields during the night. A population-based case-control study was used, covering the whole of the former West Germany. Residential magnetic fields were measured over 24 hr for 514 children with acute leukaemia identified by the German Childhood Cancer Registry and 1,301 control children taken from population registration files. Magnetic fields above 0.2 μT were relatively rare in Germany (only 1.5% of the study population). Childhood leukaemia and 24 hr median magnetic fields were only weakly related (OR = 1.55, 95% CI 0.65–3.67). A significant association was seen between childhood leukaemia and magnetic field exposure during the night (OR = 3.21, 95% CI 1.33–7.80). A dose-response-relationship was observed after combining the data of all German studies on magnetic fields and childhood leukaemia. The evidence for an association between childhood leukaemia and magnetic field eposure in our study comes from a measure of exposure during the night. Despite the large size of our study, the results are based on small numbers of exposed children. If the observed association stands, the effect on a population level in Germany would be small. © 2001 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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