Impression cytologic analysis after corneal cross-linking and insertion of corneal ring segments for keratoconus: two-year results
| Autor: | Adimara da Candelaria Renesto, Jeison de Nadai Barros, Mauro Campos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Corneal surgery laser Corneal stroma medicine.medical_treatment Riboflavin Visual Acuity Cornea lcsh:Ophthalmology Cytology Prospective Studies Cirurgia da córnea a laser Photosensitizing Agents Intrastromal corneal ring segment General Medicine Middle Aged Ceratocone Combined Modality Therapy Exact test Cross-Linking Reagents Treatment Outcome medicine.anatomical_structure Cytological techniques Riboflavina Female Adult Keratoconus medicine.medical_specialty Conjunctiva Adolescent Substância própria Prosthesis Implantation Young Adult Ophthalmology Técnicas citológicas medicine Humans Goblet cell business.industry Corneal Topography medicine.disease eye diseases Surgery Córnea lcsh:RE1-994 sense organs business |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Vol 75, Iss 2, Pp 101-106 (2012) Arquivos Brasileiros de Oftalmologia v.75 n.2 2012 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO Arquivos Brasileiros de Oftalmologia, Volume: 75, Issue: 2, Pages: 101-106, Published: APR 2012 |
| ISSN: | 1678-2925 |
| Popis: | PURPOSE: To report the impression cytologic results after corneal cross-linking and insertion of intrastromal corneal ring segments for keratoconus. METHODS: Thirty-nine eyes were distributed into two groups: 1) cross-linking group (patients underwent corneal cross-linking procedure), and 2) riboflavin eyedrops group (patients received 0.1% riboflavin (w/v) eyedrops in 20% dextran solution for 1 month). After 3 months, all patients underwent insertion of intrastromal corneal ring segments. Impression cytologic specimens were obtained from all eyes at baseline, at 1 month and 3 months after cross-linking or riboflavin eyedrops, and again at 6 months, 1 year, and 2 years after intrastromal corneal ring segment insertion. RESULTS: Patients in the cross-linking group demonstrated improvement in the cell-to-cell contact of epithelial cells and the nucleus-to-cytoplasm ratio on the temporal conjunctiva after treatment (P=0.008 and P=0.047), respectively. On the superior conjunctiva, increases in goblet cell density (P=0.037) and level of organization of nuclear chromatin (P=0.010) after treatment were noted. Patients in the riboflavin eyedrops group demonstrated improvement in the cell-to-cell contact of epithelial cells on the superior conjunctiva after treatment (P=0.021). On the temporal conjunctiva, an improvement in the cell-to-cell contact of epithelial cells (P |
| Databáze: | OpenAIRE |
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