Estrogen Replacement in Young Hypogonadal Women—Transferrable Lessons From the Literature Related to the Care of Young Women With Premature Ovarian Failure and Transgender Women
| Autor: | Usman Javaid, Du Soon Swee, Richard Quinton |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Opinion medicine.drug_class Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism ethinyl estradiol (EE) premature ovarian failure lcsh:Diseases of the endocrine glands. Clinical endocrinology Transgender women 03 medical and health sciences 0302 clinical medicine Sex hormone-binding globulin Endocrinology cross-sex hormonal treatment Transgender medicine estrogen (17b-estradiol) hormonal replacement therapy Estrogen replacement Intensive care medicine Stroke conjugated estrogen female hypogonadism lcsh:RC648-665 biology business.industry medicine.disease transgender Premature ovarian failure 030104 developmental biology Estrogen biology.protein Hormone therapy business |
| Zdroj: | Frontiers in Endocrinology Frontiers in Endocrinology, Vol 10 (2019) |
| ISSN: | 1664-2392 |
| Popis: | Nearly two decades have passed since the release of Women's Health Initiative (WHI) postmenopausal hormone therapy trial findings, yet the medical community, and general public remain unsettled by ongoing debate over the benefits and safety of sex hormone replacement therapy (HRT). Among the contentious issues is the elevated risk of venous thromboembolism (VTE) and stroke observed in HRT users (1). While major guidelines rightly recommend the use of transdermal estradiol in women with risk factors, little attention has been given to the potential impact of the type of estrogen molecule. This review aims to highlight the importance of selecting appropriate estrogen therapy to enhance safety. |
| Databáze: | OpenAIRE |
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