Preparation and biocompatibility of novel UV-curable chitosan derivatives

Autor:	Saburo Minami, Yoshihiro Shigemasa, Eiko Renbutsu, Masaru Hirose, Yasuhiko Okamura, Yoshiharu Okamoto, Hiroyuki Saimoto, Yoshihiko Omura, Fumiaki Nakatsubo
Rok vydání:	2005
Předmět:	Magnetic Resonance Spectroscopy Time Factors Polymers and Plastics Biocompatibility Light Neutrophils Ultraviolet Rays Molecular Sequence Data Bioengineering Biocompatible Materials Biomaterials Chitosan chemistry.chemical_compound Mice Random Allocation Implants Experimental In vivo Polymer chemistry Materials Testing Spectroscopy Fourier Transform Infrared Materials Chemistry medicine Animals Irradiation Cyanoacrylates Histological examination Skin Inflammation Aldehydes Biomaterial Fibroblasts medicine.disease Cellular infiltration chemistry Carbohydrate Sequence Models Chemical Female Implant Epidermis Biomedical engineering
Zdroj:	Biomacromolecules. 6(5)
ISSN:	1525-7797
Popis:	UV-curable chitosans (UVCC-7-10) were synthesized using less-toxic agents. The UVCC-7 was completely cured by UV spot irradiation for 4 s. The UVCC-7 was implanted into murine subcutaneous tissues, and the response to the implantation was observed by histological examination at 7 days after implantation. In the histological findings, the implant was surrounded by thin fibrous granulating tissue with no inflammatory cellular infiltration. Fibroblasts infiltrate between the cured implant. The novel synthesized UVCC-7 showed good biocompatibility.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739073ccd776f011fc11258cfca91ed https://pubmed.ncbi.nlm.nih.gov/16153072 Zobrazit plný text záznamu