Race/Ethnic and Educational Disparities in the Association Between Pathogen Burden and a Laboratory-Based Cumulative Deficits Index
| Autor: | Harvey J. Cohen, Grace A. Noppert, Angela M. O'Rand, Allison E. Aiello |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Health (social science) Sociology and Political Science National Health and Nutrition Examination Survey Ethnic group Article 03 medical and health sciences Race (biology) Young Adult 0302 clinical medicine Epidemiology Blood-Borne Pathogens Ethnicity Medicine Humans 030212 general & internal medicine Association (psychology) Pathogen Poverty 030505 public health business.industry Health Policy Racial Groups Public Health Environmental and Occupational Health Health Status Disparities Middle Aged Health Surveys United States Disadvantaged Socioeconomic Factors Anthropology Biomarker (medicine) Educational Status Female 0305 other medical science business Laboratories Biomarkers Demography |
| Zdroj: | J Racial Ethn Health Disparities |
| ISSN: | 2196-8837 |
| Popis: | BACKGROUND: Disparities in adult morbidity and mortality may be rooted in patterns of biological dysfunction in early life. We sought to examine the association between pathogen burden and a cumulative deficits index (CDI), conceptualized as a pre-clinical marker of an unhealthy biomarker profile, specifically focusing on patterns across levels of social disadvantage. METHODS: Using data from the National Health and Nutrition Examination Survey 2003-2004 wave (aged 20-49 years), we examined the association of pathogen burden, composed of seven pathogens with the CDI. The CDI was comprised of 28 biomarkers corresponding to available clinical laboratory measures. Models were stratified by race/ethnicity and education level. RESULTS: The CDI ranged from 0.04 to 0.78. Nearly half of Blacks were classified in the high burden pathogen class compared to 8% of Whites. Among both Mexican Americans and other Hispanic groups, the largest proportion of individuals were classified in the common pathogens class. Among educational classes, 19% of those with less than a high school education were classified in the high burden class compared to 7% of those with at least a college education. Blacks in the high burden pathogen class had a CDI 0.05 greater than those in the low burden class (P |
| Databáze: | OpenAIRE |
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