The multifactorial role of ATP in repair processes and radioprotection
| Autor: | D. Szeinfeld |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Repair processes
DNA Repair DNA repair Cells Radiation-Protective Agents Endogeny General Medicine Biology Models Biological Cell biology Cell membrane chemistry.chemical_compound Adenosine Triphosphate medicine.anatomical_structure chemistry medicine Animals Energy Metabolism Receptor Adenosine triphosphate Function (biology) Homeostasis |
| Zdroj: | Medical Hypotheses. 32:225-229 |
| ISSN: | 0306-9877 |
| DOI: | 10.1016/0306-9877(90)90127-z |
| Popis: | Endogenous ATP as a source of energy appears to play an important role associated with repair processes after ionising radiation damage in living organisms. Also exogenous ATP can play a central part in radioprotection. This paper considers interaction between the multifactorial roles of ATP in radioprotection and metabolic provision for repair processes, which can depend on its physiological regulatory function as a neuromodulator via cell membrane receptors. It is hypothesised that all these complex functions reflect an adaptive defence mechanism, against radiation insults, in which ATP plays a pivotal role to maintain homeostasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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