Somato-dendritic synapses in the nucleus reticularis thalami of the rat

Autor: Elizabeth Knyihár-Csillik, Arpad Palfi, Bertalan Csillik, Karoly Gulya, András Mihály
Rok vydání: 2002
Předmět:
Zdroj: Acta Biologica Hungarica. 53:33-41
ISSN: 0236-5383
DOI: 10.1556/abiol.53.2002.1-2.5
Popis: In the reticular nucleus of the rat thalamus, about 30% of the synapses are brought about by the perikarya of parvalbumin-immunopositive neurons, which establish somato-dendritic synapses with large dendrites of nerve cells of specific thalamic nuclei. Although the parvalbumin-immunopositive presynaptic structures bear resemblance to goblet-like or calyciform axonal endings, electron microscopic immunocytochemistry and in situ hybridization revealed that these structures are parts of the perikaryal cytoplasm studded with synaptic vesicles. In about 15% of the somato-dendritic synapses, axons are seen to be in synaptic contact with the parvalbumin-immunoreactive perikaryon. Double immunohistochemical staining revealed that the parvalbumin immunoreactive presynaptic perikarya and dendrites contained GABA. It is assumed that the peculiar somato-dendritic synaptic complexes subserve the goal of filtration of impulses arriving at the reticular nucleus from various thalamic nuclei, thus processing them for further sampling.
Databáze: OpenAIRE