Somato-dendritic synapses in the nucleus reticularis thalami of the rat
Autor: | Elizabeth Knyihár-Csillik, Arpad Palfi, Bertalan Csillik, Karoly Gulya, András Mihály |
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Rok vydání: | 2002 |
Předmět: |
Immunocytochemistry
Thalamus In situ hybridization Synaptic vesicle General Biochemistry Genetics and Molecular Biology medicine Animals Rats Wistar Microscopy Immunoelectron In Situ Hybridization gamma-Aminobutyric Acid General Environmental Science biology Chemistry Dendrites Immunohistochemistry Rats Parvalbumins medicine.anatomical_structure nervous system Neurology Cytoplasm Thalamic Nuclei Synapses Reticular connective tissue biology.protein Neuroscience Nucleus Parvalbumin |
Zdroj: | Acta Biologica Hungarica. 53:33-41 |
ISSN: | 0236-5383 |
DOI: | 10.1556/abiol.53.2002.1-2.5 |
Popis: | In the reticular nucleus of the rat thalamus, about 30% of the synapses are brought about by the perikarya of parvalbumin-immunopositive neurons, which establish somato-dendritic synapses with large dendrites of nerve cells of specific thalamic nuclei. Although the parvalbumin-immunopositive presynaptic structures bear resemblance to goblet-like or calyciform axonal endings, electron microscopic immunocytochemistry and in situ hybridization revealed that these structures are parts of the perikaryal cytoplasm studded with synaptic vesicles. In about 15% of the somato-dendritic synapses, axons are seen to be in synaptic contact with the parvalbumin-immunoreactive perikaryon. Double immunohistochemical staining revealed that the parvalbumin immunoreactive presynaptic perikarya and dendrites contained GABA. It is assumed that the peculiar somato-dendritic synaptic complexes subserve the goal of filtration of impulses arriving at the reticular nucleus from various thalamic nuclei, thus processing them for further sampling. |
Databáze: | OpenAIRE |
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