Spine Myeloid Sarcoma: A Case Series with Review of Literature

Autor: Kajal, Shah, Harsha, Panchal, Apurva, Patel
Rok vydání: 2021
Předmět:
Zdroj: South Asian Journal of Cancer, Vol 10, Iss 04, Pp 251-254 (2021)
South Asian Journal of Cancer
ISSN: 2278-4306
2278-330X
DOI: 10.1055/s-0041-1742079
Popis: Myeloid sarcoma (MS) is a malignant extramedullary tumor consisting of immature cells of myeloid origin. It may precede, present concurrently or follow acute myeloid leukemia (AML) in de novo case or may also be present and might be the only manifestation of recurrent AML, myelodysplastic syndrome, or chronic myeloid leukemia. It frequently involves skin, orbit, bone, periosteum, lymph nodes, and gastrointestinal tract, soft tissue, central nervous system, and testis. Because of its different localization and symptoms, and the lack of diagnostic algorithm, MS is a real diagnostic challenge particularly in patients without initial bone marrow involvement. The correct diagnosis of MS is important for optimum therapy, which is often delayed because of a high misdiagnosis rate. We reported three cases of MS derived from spine presented with back pain, paraplegia, paraparesis, respectively, and reviewed the relevant literature.
Databáze: OpenAIRE