Association between obesity and periodontal risk indicators in adolescents

Autor: Thomas Modéer, Claude Marcus, Tulay Lindberg, Cecilia C. Blomberg, Biniyam Wondimu
Rok vydání: 2011
Předmět:
Male
Adolescent
Cross-sectional study
Interleukin-1beta
Alveolar Bone Loss
Dental Plaque
Dentistry
Disease
Risk Assessment
Body Mass Index
Risk Factors
Surveys and Questionnaires
Environmental health
Plasminogen Activator Inhibitor 1
Odds Ratio
Humans
Periodontal Pocket
Medicine
Obesity
Child
Periodontal Diseases
Sweden
Analysis of Variance
Chi-Square Distribution
Nutrition and Dietetics
Tumor Necrosis Factor-alpha
business.industry
Health Policy
Interleukin-8
Public Health
Environmental and Occupational Health
Case-control study
Gingival Crevicular Fluid
Odds ratio
medicine.disease
Gingivitis
Cross-Sectional Studies
Logistic Models
Case-Control Studies
Pediatrics
Perinatology and Child Health
Female
Adiponectin
Inflammation Mediators
business
Risk assessment
Chi-squared distribution
Body mass index
Zdroj: International Journal of Pediatric Obesity. 6:e264-e270
ISSN: 1747-7174
1747-7166
DOI: 10.3109/17477166.2010.495779
Popis: In a cross-sectional study design we test the hypothesis of whether obesity in adolescence is associated with periodontal risk indicators or disease.Obese adolescents (n=52) and normal weight subjects (n=52) with a mean age of 14.5 years were clinically examined with respect to dental plaque, gingival inflammation, periodontal pockets and incipient alveolar bone loss. The subjects answered a questionnaire concerning medical conditions, oral hygiene habits, smoking habits and sociodemographic background. Body mass index (BMI) was calculated and adjusted for age and gender (BMI-SDS). Samples of gingival crevicular fluid (GCF) were analyzed for the levels of adiponectin, plasminogen activator inhibitor-1 (PAI-1), interleukin-1β (IL-β), interleukin-8 (IL-8) and tumor necrosis factor α (TNF-α).Obese subjects exhibited more gingival inflammation (P0.001) and more pathological periodontal pockets (4 mm) (P0.001) but not incipient alveolar bone loss compared with the normal weight subjects. Higher levels of IL-1β (P0.001) and IL-8 (P=0.002) were measured in GCF from obese subjects compared with the controls. In a multivariate logistic regression analysis, adjusted BMI-SDS (P=0.03; Odds Ratio [OR]=1.87) was significantly associated with the occurrence of pathological periodontal pockets.The study demonstrates an association between obesity and periodontal risk indicators in adolescents that in the long term may lead to oral morbidity. This result further strengthens obesity's negative effect on teenagers' periodontal health and highlights the importance of a close collaboration between dentists and pediatricians in the prevention and treatment of obesity.
Databáze: OpenAIRE
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