Conjunctival Bleeding After Ectropion Repair Due to Paraneoplastic Primary Fibrinolysis
| Autor: | Milap P. Mehta, Julian D. Perry, Theodore A. Pasquali |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Ectropion Ophthalmologic Surgical Procedures Postoperative Hemorrhage Conjunctival Diseases Prostate cancer Fibrinolytic Agents Fibrinolysis medicine Humans Aged 80 and over Aminocaproates Prostatectomy Factor VIII Paraneoplastic Syndromes Ocular business.industry Eyelids Fibrinogen Prostatic Neoplasms Cancer General Medicine medicine.disease Combined Modality Therapy Thrombosis Surgery Bleeding diathesis Ophthalmology Radiotherapy Adjuvant Fresh frozen plasma Erythrocyte Transfusion business Complication |
| Zdroj: | Ophthalmic Plastic & Reconstructive Surgery. 28:e44-e45 |
| ISSN: | 0740-9303 |
| DOI: | 10.1097/iop.0b013e31821de7ff |
| Popis: | In addition to predisposing a patient to hypercoaguability and thrombosis, cancers may also cause an antithetical bleeding diathesis through primary fibrinolysis. This paraneoplastic pathology has been documented and studied in prostate cancer patients for nearly a century but is under-recognized as a possible complication of surgery. We report a case of primary fibrinolysis after elective ectropion repair in a patient with prostate cancer. Here paraneoplastic fibrinolysis produced a delayed postoperative hemorrhage requiring specialized therapies, including hospitalization for transfusions of fresh frozen plasma and inhibitors of fibrinolysis. Even in the case of an ambulatory and stable cancer patient, awareness of this complication and its management can help guide surgical decision-making and improve outcomes and follow-up care. |
| Databáze: | OpenAIRE |
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