Seasonal variation of kaurenoic acid, a hypoglycemic diterpene present in Wedelia paludosa (Acmela brasiliensis) (Asteraceae)
Autor: | Kauê Leal Bóf, Valdir Cechinel-Filho, Cristiani Bürger, Rosendo A. Yunes, Luis Eduardo De Oliveira, Louisiane F.V. Bresciani |
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Rok vydání: | 2004 |
Předmět: |
Blood Glucose
Male Biology General Biochemistry Genetics and Molecular Biology Wedelia chemistry.chemical_compound Botany Kaurenoic acid Glyburide medicine Animals Hypoglycemic Agents Rats Wistar Plant Extracts Seasonality Asteraceae Glucose Tolerance Test medicine.disease biology.organism_classification Rats chemistry Hyperglycemia Seasons Diterpene Diterpenes |
Zdroj: | Zeitschrift fur Naturforschung. C, Journal of biosciences. 59(3-4) |
ISSN: | 0939-5075 |
Popis: | We evaluated the variation of the concentration of kaurenoic acid (1), which is a bioactive diterpene, in leaves, flowers, stems and roots from Wedelia paludosa (Acmela brasiliensis) for different seasons using the HRGC/FID method. The results indicated that the concentration of 1 is higher in the roots and stems during the autumn. The pharmacological results suggested that kaurenoic acid is responsible, at least in part, for the hypoglycemic potential detected in this plant. |
Databáze: | OpenAIRE |
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