Finally an evidence-based indication for injectable phloroglucinol!
| Autor: | Caroline Simon Toulza, Fabien Vidal, Lola Loussert, Paul Guerby |
|---|---|
| Přispěvatelé: | Hôpital Paule de Viguier, CHU Toulouse [Toulouse], Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Clinique rive gauche, CCSD, Accord Elsevier |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Efficacy [SDV]Life Sciences [q-bio] Phloroglucinol Stain Placebo law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Randomized controlled trial law Medicine Stain remover Povidone-Iodine 030219 obstetrics & reproductive medicine business.industry White coat Obstetrics and Gynecology Active control 3. Good health Surgery [SDV] Life Sciences [q-bio] Injectable phloroglucinol Reproductive Medicine chemistry 030220 oncology & carcinogenesis business After treatment |
| Zdroj: | Journal of Gynecology Obstetrics and Human Reproduction Journal of Gynecology Obstetrics and Human Reproduction, Elsevier, 2019, 48, pp.825-826. ⟨10.1016/j.jogoh.2019.04.008⟩ Journal of Gynecology Obstetrics and Human Reproduction, 2019, 48, pp.825-826. ⟨10.1016/j.jogoh.2019.04.008⟩ |
| ISSN: | 2468-7847 |
| Popis: | International audience; Background: While phloroglucinol is widely prescribed in European countries for its antispasmodic properties, recent high quality data failed to demonstrate its superiority to placebo in alleviating abdominal pain. Rumors suggest that injectable presentation of phloroglucinol may erase povidone-iodine stains. We thus aimed to evaluate its efficacy in this new indication.Methods: In this double-blind, controlled trial, we randomly assigned 9 squares of fabric obtained from common white coat to receive injectable phloroglucinol (experimental arm), stain remover (active control arm) or water (placebo arm). The primary efficacy endpoint was the change in stain intensity 10 min after the intervention.Results: In placebo and active control arms, povidone-iodine stains remained unchanged 10 min after treatment application. In contrast, the stain disappeared completely in the experimental arm.Conclusion: Injectable phloroglucinol was more effective than usual stain remover and water to remove povidone-iodine stains from white coats. |
| Databáze: | OpenAIRE |
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