BIRADS 3 MRI lesions: Was the initial score appropriate and what is the value of the blooming sign as an additional parameter to better characterize these lesions?
| Autor: | Nathalie Faye, Luc Ceugnart, Ralphy Guillaume, Valerie Deken-Delannoy, Sophie Taïeb |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Pathology Breast Neoplasms Malignancy Sensitivity and Specificity 030218 nuclear medicine & medical imaging Lesion 03 medical and health sciences 0302 clinical medicine Late phase medicine Humans Breast MRI Radiology Nuclear Medicine and imaging Aged Retrospective Studies medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Predictive value Size increase 030220 oncology & carcinogenesis Female Radiology medicine.symptom business Sign (mathematics) |
| Zdroj: | European Journal of Radiology. 85:337-345 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2015.11.032 |
| Popis: | Objective To investigate whether there were suspicious criteria on the initial MRI in BIRADS 3 lesions. To analyze the value of “blooming sign” as an additional criterion for malignancy. Materials and methods In this retrospective study the lesion morphological and enhancement characteristics were analyzed. The “blooming sign” (BS), defined as the lesion size increase between the early and the late phase after gadolinium was assessed. We determined the optimal cut-off value for the BS to distinguish benign and malignant breast lesions. Results 100 lesions were classified BIRADS 3 in 75 patients (12%). Four of the five malignant lesions had suspicious BIRADS criteria on the index MRI. 45 lesions were stable and 30 lesions resolved spontaneously during the follow-up MRI. The optimal cut-off value for the BS was 8.54% with 100% sensitivity, 94% specificity, 44% positive and 100% negative predictive values. Using reclassification rule to upgrade benign BIRADS lesions with suspicious BS feature and downgrade suspicious BIRADS lesions with benign BS feature increased MRI specificity (89%), sensitivity (100%) while preserving NPV (100%). Conclusions This study showed the suggestive part of classified BIRADS 3 lesions. The blooming sign seems to be a good additional parameter to increase MRI specificity when associated to BIRADS criteria. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect