Clinical Outcomes of Pediatric Ventricular Assist Device Implantation: A Single-Institute Report from Japan
| Autor: | Masahide Komagamine, Tomohiro Nishinaka, Yusuke Iwata, Hiroyuki Tsukui, Yuki Ichihara, Satoshi Saito, Kenji Yamazaki |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Treatment outcome Biomedical Engineering Time to treatment Medicine (miscellaneous) Bioengineering Prosthesis Design Severity of Illness Index Ventricular Function Left Time-to-Treatment Biomaterials Japan Severity of illness medicine Humans Prosthesis design Child Intensive care medicine Heart Failure Heart transplantation business.industry Age Factors General Medicine medicine.disease Treatment Outcome Ventricular assist device Heart failure Heart Transplantation Female Heart-Assist Devices Pediatric heart transplantation business |
| Zdroj: | The International Journal of Artificial Organs. 36:887-891 |
| ISSN: | 1724-6040 0391-3988 |
| DOI: | 10.5301/ijao.5000263 |
| Popis: | Purpose Numerous difficulties remain associated with pediatric heart transplantation. Therefore, the development of a ventricular assist device (VAD) specific to these cases is extremely important for therapeutic effectiveness. We present 5 cases of severe heart failure that were managed by ventricular assist device implantation, as a bridge to transplantation. Methods We examined the clinical course of 5 patients (4 boys, 1 girl; mean age, 10.6 ± 1.5 years; range, 8-12 years) who underwent implantation of a pneumatic extracorporeal ventricular assist device between February 2004 and May 2009. Four patients had dilated cardiomyopathy and one had corrected transposition of the great arteries. Results The mean period between onset of heart failure and ventricular assist device implantation was 594 ± 750 days (range, 94-1702 days), and the mean duration of ventricular assist support was 112 ± 98 days (range, 44-284 days). Four patients underwent heart transplantation overseas and one died of cerebral hemorrhage. Conclusions Careful management of pediatric VAD patients and development of a device designed specifically for pediatric patients are essential for improving clinical outcomes in the future. |
| Databáze: | OpenAIRE |
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