Hepatitis C among child transfusion and adult renal dialysis patients in Indonesia
| Autor: | Kanti Laras, H Ali Sulaiman, Widodo Soeprapto, Ratna Tan, James R. Campbell, Annie Sie, Nono Sukri, Andrew L. Corwin, G Fraser Chanpong, S Purnamawati |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion Adolescent medicine.medical_treatment Hepacivirus Renal Dialysis Risk Factors Virology Internal medicine Surveys and Questionnaires Epidemiology medicine Prevalence Seroprevalence Humans Risk factor Child Aged business.industry Infant Transfusion Reaction Odds ratio Hepatitis C Jaundice Hepatitis C Antibodies Middle Aged medicine.disease Surgery Infectious Diseases Indonesia Case-Control Studies Child Preschool Parasitology Hemodialysis medicine.symptom business |
| Zdroj: | The American journal of tropical medicine and hygiene. 66(3) |
| ISSN: | 0002-9637 |
| Popis: | Hepatitis C virus (HCV) prevalence among high-risk pediatric and adult patients was evaluated. The study included 269 adults and 150 children in a case-control research design. Risk factors of HCV exposure in Indonesia were assessed among adult renal dialysis patients and pediatric patients who received multiple blood transfusions. A high prevalence of anti-HCV was found among the adult renal dialysis patients, measured by second-generation electroimmunoassay tests. Family members of dialysis patients, who served as a comparison group for dialysis patients, were found to have a 9.0% seroprevalence. The prevalence of anti-HCV among pediatric patients with hematological disorders was found to be 39.0%. The comparison group seroprevalence (pediatric patients and family members) was 4.3% among sera available for confirmatory testing. Patients with history of hospitalization (odds ratio [OR] = 7.94, 95% confidence interval [CI]: 4.06-15.51, P = 0.0001), blood transfusion (OR = 6.85, 95% CI: 3.95-11.88, P = 0.0001), circumcision (OR = 2.39, 95% CI: 1.43-3.99, P = 0.0001), or marital partner/family member history of jaundice (OR = 3.62, 95% CI: 1.97-6.62, P = 0.0001) were found to have an increased odds of HCV exposure compared with individuals without similar histories. |
| Databáze: | OpenAIRE |
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