Airway wall splice quantitative trait locus analysis reveals novel downstream mechanisms for known asthma single-nucleotide polymorphisms

Autor: Tessa M. Kole, Simon D. Pouwels, Rene Bults, Marlies E. Ketelaar, Victor Guryev, Lisanne Koll, Huib A.M. Kerstjens, Martijn C. Nawijn, Alen Faiz, Maarten van den Berge
Přispěvatelé: Groningen Research Institute for Asthma and COPD (GRIAC)
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ERJ Open Research, 9(2):00413-2022. European Respiratory Society
ISSN: 2312-0541
Popis: Studying the effects of asthma SNPs on alternative splicing can lead to new insights into asthma pathophysiology. More specifically, a 17q12 SNP is associated to alternative splicing of GSDMB. https://bit.ly/3W49oTs.
Databáze: OpenAIRE