Long-term follow-up of an amblyopia treatment study: change in visual acuity 15 years after occlusion therapy
Autor: | Huibert J. Simonsz, Brigitte Simonsz-Tóth, Bronte M Janszen, Joost van Rosmalen, Sanne J M Pijnenburg, Aveen Kadhum, Sjoukje E. Loudon |
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Přispěvatelé: | University of Zurich, Loudon, Sjoukje E, Ophthalmology, Epidemiology |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
10018 Ophthalmology Clinic
Male medicine.medical_specialty Visual acuity Adolescent visual acuity genetic structures Visual impairment Population 610 Medicine & health Amblyopia 03 medical and health sciences 0302 clinical medicine Ophthalmology medicine Humans Cover test Prospective Studies Child education Anisometropia Vision Binocular education.field_of_study business.industry Original Articles General Medicine 2731 Ophthalmology medicine.disease Subjective refraction eye diseases Treatment Outcome Child Preschool long‐term follow‐up occlusion therapy Fixation (visual) Disease Progression 030221 ophthalmology & optometry Female Original Article Sensory Deprivation medicine.symptom business Orthoptic 030217 neurology & neurosurgery Follow-Up Studies Forecasting |
Zdroj: | Acta Ophthalmologica Acta Ophthalmologica, 99(1), E36-E42. Wiley-Blackwell Publishing Ltd |
ISSN: | 1755-3768 1755-375X |
Popis: | Purpose: To determine change in visual acuity (VA) in the population of a previous amblyopia treatment study (Loudon 2006) and assess risk factors for VA decrease. Methods: Subjects treated between 2001 and 2003 were contacted between December 2015 and July 2017. Orthoptic examination was conducted under controlled circumstances and included subjective refraction, best corrected VA, reading acuity, binocular vision, retinal fixation, cover-uncover and alternating cover test. As a measure for degree of amblyopia, InterOcular VA Difference (IOD) at the end of occlusion therapy was compared with IOD at the follow-up examination using Wilcoxon’s signed-rank test. Regression analysis was conducted to determine the influence of clinical and socio-economic factors on changes in IOD. Results: Out of 303 subjects from the original study, 208 were contacted successfully, 59 refused and 15 were excluded because of non-amblyopic cause of visual impairment. Mean IOD at end of therapy (mean age 6.4 years) was 0.11 ± 0.16 logMAR, and IOD at follow-up examination (mean age 18.3 years) was 0.09 ± 0.21 logMAR; this difference was not significant (p = 0.054). Degree of anisometropia (p = 0.008; univariable analysis), increasing anisometropia (p = 0.009; multivariable), eccentric fixation (p |
Databáze: | OpenAIRE |
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