Heme Inhibition of Ferrisiderophore Reductase in Bacillus subtilis
| Autor: | C. G. Gaines, Jean E. L. Arceneaux, B. R. Byers, J. S. Lodge |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1982 |
| Předmět: |
Protoporphyrin IX
biology Physiology and Metabolism Metabolism Bacillus subtilis Heme Reductase biology.organism_classification Microbiology Iron assimilation chemistry.chemical_compound Kinetics Structure-Activity Relationship Non-competitive inhibition chemistry Biochemistry Structure–activity relationship NADH NADPH Oxidoreductases Oxidoreductases Molecular Biology |
| Popis: | Heme was a noncompetitive inhibitor (apparent K i and K′ i = 0.043 mM) of a ferrisiderophore reductase purified from Bacillus subtilis ; protoporphyrin IX had no effect. The cellular level of heme may partly regulate the function of this reductase to yield a controlled flow of iron into metabolism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|