Reconstruction versus no reconstruction of iliac crest defects following harvest for spinal fusion: a systematic review

Autor: Anthony Minh Tien Chau, Cristian Gragnaniello, Ralph J. Mobbs, Lileane L. Xu, Ralph Stanford, Rhys Gordon van der Rijt, Johnny Ho-Yin Wong
Rok vydání: 2012
Předmět:
Zdroj: Journal of Neurosurgery: Spine. 16:565-572
ISSN: 1547-5654
DOI: 10.3171/2012.3.spine11979
Popis: ObjectAutologous bone from the iliac crest is commonly used for spinal fusion. However, its use is associated with significant donor site morbidity, especially pain. Reconstructive procedures of the iatrogenic defect have been investigated as a technique to alleviate these symptoms. The goal of this study was to assess the effects of reconstruction versus no reconstruction following iliac crest harvest in adults undergoing spine surgery.MethodsThe authors searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2011, Issue 4); MEDLINE (1948–Oct 2011); EMBASE (1947–Oct 2011); and the reference lists of articles. Randomized controlled trials (RCTs) or nonrandomized controlled trials (NRCTs) were included in the study. Two independent reviewers selected the studies, extracted data using a standardized collection form, and assessed for risk of bias.ResultsThree RCTs (96 patients) and 2 NRCTs (82 patients) were included. These had a moderate to high risk of bias. The results suggest that iliac crest reconstruction may be useful in reducing postoperative pain, minimizing functional disability, and improving cosmesis. No pattern of other clinical, radiological, or resource outcomes was identified.ConclusionsAlthough the available evidence is suboptimal, this systematic review supports the notion that iliac crest reconstruction following harvest for spinal fusion may reduce postoperative pain, minimize functional disability, and improve cosmesis.
Databáze: OpenAIRE