Ocular non-teratoid medulloepithelioma with teratoid metastases in ipsilateral intraparotid lymph nodes
| Autor: | Mehar Chand Sharma, Chirom Amit Singh, Jayati Sarangi, Rishikesh Thakur, Aanchal Kakkar, Diya Roy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Uveal Neoplasms medicine.medical_specialty Eye Enucleation 03 medical and health sciences Teratoid medulloepithelioma 0302 clinical medicine Positron Emission Tomography Computed Tomography medicine Humans Neuroectodermal Tumors Primitive Intraocular tumor Child business.industry Ciliary Body Teratoma General Medicine medicine.disease Magnetic Resonance Imaging Parotid Neoplasms Ophthalmology 030220 oncology & carcinogenesis Lymphatic Metastasis 030221 ophthalmology & optometry Neck Dissection Lymph Radiology Lymph Nodes Presentation (obstetrics) Medulloepithelioma business Neck |
| Zdroj: | European journal of ophthalmology. 31(2) |
| ISSN: | 1724-6016 |
| Popis: | Purpose: To describe a rare presentation of a case of intraocular non-teratoid medulloepithelioma with teratoid metastases in ipsilateral intraparotid lymph nodes. Case description: A 9-year-old male child with previous history of ciliary body non-teratoid medulloepithelioma presented with a swelling in the right pre-auricular region for 1 month. Magnetic resonance imaging and positron emission tomography–computed tomography showed a right intraparotid mass with enlarged ipsilateral cervical lymph nodes. A core biopsy was taken from the lesion, which on microscopy showed a tumor composed of small round cells arranged in cords, tubules lined by multilayered cells, and in cribriform pattern. These cells were embedded in a hypocellular, loose myxoid matrix. Based on the histopathological characteristics and previous history, a diagnosis of medulloepithelioma metastastic to ipsilateral parotid gland was made. The patient underwent right total conservative parotidectomy and bilateral neck dissection. Histopathological examination revealed metastatic medulloepithelioma in five out of eight intraparotid lymph nodes, with extranodal extension into the adjacent parotid parenchyma. Foci of hyaline cartilage were identified within the tumor, leading to a diagnosis of metastatic teratoid medulloepithelioma. Conclusion: Intraparotid lymph node metastases from intraocular medulloepithelioma is a rare possibility and we recommend that the parotid should be evaluated in cases of intraocular medulloepithelioma at initial presentation as well as during the follow-up period. Also, metastasis should be considered in all pediatric patients with solitary mass lesions showing unconventional histology for a primary parotid neoplasm. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|