Cognitive estimation impairment in Alzheimer disease and mild cognitive impairment
| Autor: | Nora Kelner, Howard Chertkow, Natalie A. Phillips, Lennie Babins, Vivian Akerib, Louis Verret, Elise J. Levinoff |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Psychometrics Concept Formation Short-term memory Pilot Projects Audiology Neuropsychological Tests Cohort Studies Degenerative disease Alzheimer Disease Reference Values medicine Semantic memory Humans Attention Problem Solving Aged Working memory Cognitive disorder Neuropsychology Reproducibility of Results Cognition Middle Aged Verbal Learning medicine.disease Neuropsychology and Physiological Psychology Memory Short-Term Female Alzheimer's disease Psychology Cognition Disorders Cognitive psychology |
| Zdroj: | Neuropsychology. 20(1) |
| ISSN: | 0894-4105 |
| Popis: | Intact executive functioning is believed to be required for performance on tasks requiring cognitive estimations. This study used a revised version of a cognitive estimations test (CET) to investigate whether patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) were impaired on the CET compared with normal elderly controls (NECs). Neuropsychological tests were administered to determine the relationship between CET performance and other cognitive domains. AD patients displayed impaired CET performance when compared with NECs but MCI patients did not. Negative correlations between tests of working memory (WM) and semantic memory and the CET were found in NECs and AD patients, indicating that these cognitive domains were important for CET performance. Regression analysis suggests that AD patients were unable to maintain semantic information in WM to perform the task. The authors conclude that AD patients display deficits in working memory, semantic memory, and executive function, which are required for adequate CET performance. |
| Databáze: | OpenAIRE |
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