Spatial and temporal trends of visceral leishmaniasis by mesoregion in a southeastern state of Brazil, 2002-2013

Autor: Ilka Afonso Reis, Mariângela Carneiro, David Soeiro Barbosa, Thais Almeida Marques da Silva, Bruna Dias Tourinho, Carla Sayuri Fogaça Oiko, Maria Helena Franco Morais, Wendel Coura-Vital, Diogo Portella Ornelas de Melo
Rok vydání: 2017
Předmět:
Time Factors
Urban Population
Epidemiology
Prevalence
Social Sciences
Geographical locations
0302 clinical medicine
Environmental protection
Zoonoses
Medicine and Health Sciences
Poisson Distribution
Socioeconomics
Leishmaniasis
Geographic Areas
Geography
Ecology
lcsh:Public aspects of medicine
Incidence
Incidence (epidemiology)
Eukaryota
Infectious Diseases
symbols
Leishmaniasis
Visceral
Regression Analysis
0305 other medical science
Brazil
Research Article
Neglected Tropical Diseases
Urban Areas
lcsh:Arctic medicine. Tropical medicine
Infectious Disease Control
lcsh:RC955-962
Animal Types
030231 tropical medicine
Notifiable disease
Human Geography
Urban Geography
Kala-Azar
03 medical and health sciences
symbols.namesake
Dogs
Parasitic Diseases
medicine
Animals
Humans
Domestic Animals
Poisson regression
Spatial Analysis
Protozoan Infections
030505 public health
Organisms
Public Health
Environmental and Occupational Health
Biology and Life Sciences
Ecological study
lcsh:RA1-1270
South America
Tropical Diseases
medicine.disease
Metropolitan area
Visceral leishmaniasis
Earth Sciences
Linear Models
Spatial variability
People and places
Zoology
Zdroj: PLoS Neglected Tropical Diseases
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0005950 (2017)
ISSN: 1935-2735
1935-2727
DOI: 10.1371/journal.pntd.0005950
Popis: Background Visceral leishmaniasis (VL) is expanding in Brazil and in other South American countries, a process that has been associated with the urbanization of the disease. This study analyzes the spatial and temporal distribution of VL in the Brazilian state of Minas Gerais and identifies the areas with higher risks of transmission. Methodology An ecological study with spatial and time series analyzes of new confirmed cases of VL notified to the Brazilian Notifiable Disease Information System between 2002 and 2013, considering the 12 mesoregions of Minas Gerais. Two complementary methodologies were used: thematic maps of incidence and Poisson (log-linear) generalized linear model. Thematic maps using crude and smoothed cumulative incidences were generated for four trienniums. Poisson Regression measured the variation of the average number of cases from one year to the following, for each mesoregion. Principal findings The 5,778 cases analyzed revealed a heterogeneous spatial and temporal distribution of VL in Minas Gerais. Six mesoregions (Central Mineira, Jequitinhonha, Metropolitan area of Belo Horizonte, Northwest of Minas, North of Minas, and Vale do Rio Doce) were responsible for the expansion and maintenance of VL, with incidence rates as high as 26/100,000 inhabitants. The Vale do Rio Doce and Jequitinhonha mesoregions showed a considerable increase in the incidence rates in the last period studied. The other six mesoregions reported only sporadic cases and presented low and unsteady incidence rates, reaching a maximum of 1.2/100,000 inhabitants. Conclusions/Significance The results contribute to further the current understanding about the expansion of VL in Minas Gerais and may help guide actions for disease control.
Author summary This article presents the spatial and temporal distribution of visceral leishmaniasis (VL) in Minas Gerais State and identifies the greater risk areas of transmission. This study is both timely and substantive because Minas Gerais is an important Brazilian state in the number of cases of visceral leishmaniasis. The results showed that during the 12-year time series the VL had a heterogeneous spatial and temporal distribution in the state of Minas Gerais. Among the 12 existing mesoregions, six (Central Mineira, Jequitinhonha, Metropolitan area of Belo Horizonte, Northwest of Minas, North of Minas, and Vale do Rio Doce) were responsible for the expansion and maintenance of VL in the state. Among them, the Vale do Rio Doce and Jequitinhonha mesoregions presented a considerable increase in the incidence rates of the disease in the last period. In the other six mesoregions only sporadic cases of the disease were reported during the study period. The results of in this study may contribute to a better understanding the dynamic of the disease in Minas Gerais. Also these findings can provide subsidies to assist the actions of the control program of VL.
Databáze: OpenAIRE
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