Early oral hydration protects against pharyngocutaneous fistula after total laryngectomy or total pharyngolaryngectomy
| Autor: | Laure Santini, Abdallah Alshukry, Antoine Giovanni, Matthieu Le Flem, Patrick Dessi, Carole Boulze, Nicolas Fakhry |
|---|---|
| Přispěvatelé: | Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Laboratoire Parole et Langage (LPL), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
protective factor medicine.medical_treatment Cutaneous Fistula [SDV]Life Sciences [q-bio] Laryngectomy pharyngocutaneous fistula Pharyngocutaneous Fistula early oral hydration Gastroenterology 03 medical and health sciences 0302 clinical medicine Postoperative Complications Internal medicine postlaryngectomy complications medicine Humans Prospective Studies 030223 otorhinolaryngology Laryngeal Neoplasms Retrospective Studies business.industry Incidence (epidemiology) Significant difference Retrospective cohort study Odds ratio Pharyngeal Diseases Total pharyngolaryngectomy Confidence interval 3. Good health Otorhinolaryngology 030220 oncology & carcinogenesis incidence business |
| Zdroj: | Head & Neck Head & Neck, 2020, 42 (8), pp.1902-1906. ⟨10.1002/hed.26122⟩ Head and Neck Head and Neck, Wiley, 2020, 42 (8), pp.1902-1906. ⟨10.1002/hed.26122⟩ |
| ISSN: | 1043-3074 1097-0347 |
| DOI: | 10.1002/hed.26122⟩ |
| Popis: | International audience; Background: The objective of this study was to evaluate the impact of early oral hydration on the incidence of pharyngocutaneous fistula (PCF) after total laryngectomy (TL) or total pharyngolaryngectomy (TPL).Methods: A prospective series of 25 patients operated on between October 2017 and March 2019 who received early oral hydration starting 2 days after surgery were compared to a retrospective cohort of 28 patients who did not receive any early oral hydration. These are two consecutive series including all operated patients.Results: There was no significant difference between the two groups in terms of risk factors for PCF. In univariate and multivariate analysis, early oral hydration was significantly associated with a decreased risk of PCF: 50% vs 20% (odds ratio [OR], 0.25; 95% confidence interval [95% CI], 0.07-0.85; P = .03, vs OR, 0.24; 95% CI, 0.07-0.85; P = .02).Conclusion: Early oral hydration after TL or TPL reduces the risk of PCF. |
| Databáze: | OpenAIRE |
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