| Autor: |
Sameni, Mansoureh, Cavallo-Medved, Dora, Franco, Omar, Chalasani, Anita, Kyungmin Ji, Aggarwal, Neha, Arulselvi Anbalagan, Xuequn Chen, Mattingly, Raymond, Hayward, Simon, Sloane, Bonnie |
| Rok vydání: |
2017 |
| DOI: |
10.6084/m9.figshare.c.3780431_d5 |
| Popis: |
Targeting IL-6 reduces size and invasiveness of and ECM degradation by SUM102-CAF structures formed in MAME cultures. SUM102-lentiRFP and WS-12T (CAFs) were seeded onto rBM overlaid with 2% rBM in the presence of isotype control or 100 ng/ml IL-6 neutralizing antibody (IL-6 nAb) and imaged live at day 8. Representative en face views of 3D reconstructions of SUM102 (red)-CAF (unlabeled) structures and associated dDQ-IV (green) in MAME cultures. One grid unit = 45 μm. (PDF 278 kb) |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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