Alterations of Tear Film and Ocular Surface in Children with Type 1 Diabetes Mellitus
| Autor: | Zehra Aycan, Rumeysa Hekimoglu, Elvan Bayramoğlu, Merve Inanc, Sinan Yuruker, Mustafa Koc, Kemal Tekin, Şervan Özalkak, Hasan Kiziltoprak, Selim Zırh |
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| Přispěvatelé: | Uşak Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, HEKİMOĞLU, EMİNE RÜMEYSA |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Adolescent impression cytology Slit Lamp Microscopy 03 medical and health sciences dry eye 0302 clinical medicine Ophthalmology Diabetes mellitus Surveys and Questionnaires medicine Immunology and Allergy Humans Prospective Studies Child tear film 030203 arthritis & rheumatology Type 1 diabetes ocular surface business.industry Impression cytology medicine.disease eye diseases Cross-Sectional Studies Diabetes Mellitus Type 1 Tears 030221 ophthalmology & optometry Dry Eye Syndromes Female business Ocular surface Conjunctiva mellitus |
| Zdroj: | Ocular immunology and inflammation. 28(3) |
| ISSN: | 1744-5078 |
| Popis: | Purpose: To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM. Methods: Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed. Results: Schirmer test and TBUT results were significantly lower in DM group than controls (p = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density (p > 0.05). The TBUT results were significantly associated with duration of DM (r = ?0.309, p = 0.036). Conclusion: Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups. © 2019, © 2019 Taylor & Francis Group, LLC. |
| Databáze: | OpenAIRE |
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