Multiple retinal arteriolar occlusions associated with coexisting primary antiphospholipid syndrome and factor V Leiden mutation
| Autor: | Benjamin Miller, Benjamin Brenner, Yuval A Gelfand, Naomi Lanir, Itzchak Beiran, J. Scharf, Dalia Dori |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
medicine.medical_specialty Retinal Artery Occlusion Thrombophilia chemistry.chemical_compound Internal medicine Factor V Leiden Coagulopathy Humans Point Mutation Medicine cardiovascular diseases Fluorescein Angiography Activated Protein C Resistance Retinal Vascular Occlusion Heparin business.industry Vascular disease Factor V Retinal Antiphospholipid Syndrome medicine.disease Surgery Arterioles Ophthalmology chemistry Cardiology Female Warfarin Differential diagnosis business Retinopathy |
| Zdroj: | American Journal of Ophthalmology. 129:106-108 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/s0002-9394(99)00278-0 |
| Popis: | PURPOSE: To investigate a case of a young woman with both primary antiphospholipid syndrome and factor V Leiden mutation who developed multiple retinal arteriolar occlusions. METHOD: Case report of a 25-year-old woman with history and laboratory tests confirming the diagnosis of both primary antiphospholipid syndrome and factor V Leiden mutation who presented with blurred vision in both eyes. RESULTS: Multiple retinal arteriolar occlusions were observed in both of her eyes. The patient was treated first with heparin and then with warfarin. CONCLUSIONS: Primary antiphospholipid syndrome and factor V Leiden mutation, as well as other forms of thrombophilia, should be considered in the differential diagnosis of unexplained retinal vascular occlusions. The coexistence of several thrombophilic disorders may carry a particularly high risk for thrombotic manifestations. |
| Databáze: | OpenAIRE |
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