Effect of antithrombotic therapy on postoperative outcome of 538 consecutive emergency laparoscopic cholecystectomies for acute cholecystitis: two Italian center's study
| Autor: | Maurizio Cervellera, Samuele Vaccari, Valeria Tonini, Maria Irene Bellini, Vito D'Andrea, Augusto Lauro, G Palazzini, Roberto Cirocchi |
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| Přispěvatelé: | Vaccari, Samuele, Lauro, Augusto, Cervellera, Maurizio, Bellini, Maria Irene, Palazzini, Giorgio, Cirocchi, Roberto, Tonini, Valeria, D'Andrea, Vito |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
endocrine system Multivariate analysis medicine.medical_treatment Cholecystitis Acute Blood Loss Surgical Acute cholecystiti Acute cholecystitis Anticoagulation therapy Antiplatelet therapy Antithrombotic therapy Bleeding complication Emergency cholecystectomy Laparoscopy Postoperative Complications Blood loss Fibrinolytic Agents Antithrombotic medicine Postoperative outcome Humans Retrospective Studies medicine.diagnostic_test business.industry Postoperative complication Surgery Treatment Outcome Cholecystectomy Laparoscopic Italy Cholecystectomy business |
| Popis: | The risk of developing hemorrhagic complications during or after emergency cholecystectomy (EC) for acute cholecystitis (AC) in patients with antithrombotic therapy (ATT) remains uncertain. In this double-center study, we evaluated post-operative outcomes in patients with ATT undergoing EC. We retrospectively evaluated 538 patients who underwent laparoscopic EC for AC between May 2015 and December 2019 at two referral centers. 89 of them (17%) were on ATT. We defined postoperative complication rates, including bleeding, as our primary outcome. Mortality was higher in the ATT group. Morbidity was higher in the ATT group as well; however, the difference was not statistically significant. 12 patients (2%) experienced intraoperative blood loss over 500ml and ten (2%) had postoperative bleeding complications. Two patients ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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