Spatially resolved electronic detection of biopolymers
Autor: | B. Straub, Denis Côte, Cédric Gentil, Ulrich Bockelmann, Günther Zeck, François Pouthas |
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Přispěvatelé: | Thomen, Philippe, Laboratoire Pierre Aigrain (LPA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS) |
Jazyk: | angličtina |
Rok vydání: | 2004 |
Předmět: |
Materials science
Transistors Electronic Biosensing Techniques 02 engineering and technology Electrolyte engineering.material 010402 general chemistry Sensitivity and Specificity 01 natural sciences law.invention Ion [PHYS] Physics [physics] Biopolymers law Electrochemistry Polylysine Electrodes Oligonucleotide Array Sequence Analysis [PHYS]Physics [physics] chemistry.chemical_classification business.industry Transistor Reproducibility of Results Transistor array DNA Equipment Design Polymer equipment and supplies 021001 nanoscience & nanotechnology 0104 chemical sciences Equipment Failure Analysis Semiconductor chemistry Chemical physics Electrode engineering Biopolymer 0210 nano-technology business |
Zdroj: | Physical Review E : Statistical, Nonlinear, and Soft Matter Physics Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, American Physical Society, 2004, 70, pp.031906 Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, 2004, 70, pp.031906 |
ISSN: | 1539-3755 1550-2376 |
Popis: | An integrated array of field-effect transistor structures is used to detect two oppositely charged biopolymers: poly(L-lysine) and DNA. Local deposition of polymer solutions on part of the array induces sizeable variations in the dc current-voltage characteristics of the transistors exposed to the molecular charge. The whole transistor array is measured in the presence of a common electrolyte. Differential signals are studied as a function of electrolyte salt and polymer concentrations. The measurements provide information on the interface electrostatic potentials of the (semiconductor/biopolymer/electrolyte) system and the experimental data are compared to an analytical model which accounts for screening of the adsorbed charge by mobile ions. |
Databáze: | OpenAIRE |
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