Parotid gland stem cells: Mini yet mighty
| Autor: | Mustafa Cengiz, Deniz Yuce, Sezin Yuce Sari, Melek Tugce Yilmaz, Gokhan Ozyigit, Gozde Yazici, Aysenur Elmali, Fazli Yagiz Yedekci |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment Urology Xerostomia 03 medical and health sciences 0302 clinical medicine Medicine Humans Parotid Gland Radiation treatment planning Retrospective Studies business.industry Stem Cells Head and neck cancer Radiotherapy Dosage medicine.disease Dry mouth Parotid gland Radiation therapy 030104 developmental biology medicine.anatomical_structure Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis Radiotherapy Intensity-Modulated Stem cell medicine.symptom business |
| Zdroj: | HeadneckREFERENCES. 43(4) |
| ISSN: | 1097-0347 |
| Popis: | Background Our aim was to evaluate the correlation between the radiation doses to parotid gland (PG) stem cells and xerostomia. Methods Patients diagnosed with head and neck cancer (HNC) were retrospectively evaluated, and xerostomia inventory (XI) was applied to these patients. PG stem cells were delineated on the treatment planning CT, and the mean doses to the PG stem cells calculated. Results The total test score and mean doses to bilateral PGs were significantly correlated (r = .34, P = .001), and the mean doses to bilateral PG stem cell niches were significantly correlated with the total test score (r = .32, P = .002). Conclusions In this study, we found that the mean dose to PG stem cells can predict dry mouth as much as the mean dose to the PG. |
| Databáze: | OpenAIRE |
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