Older patients (aged ≥60 years) with previously untreated advanced-stage classical Hodgkin lymphoma: a detailed analysis from the phase III ECHELON-1 study
| Autor: | Andres Forero-Torres, Tatyana Feldman, Christopher Pocock, Andrea Gallamini, John Radford, Joseph Tuscano, Yasuhiro Oki, Andrew M. Evens, Hina Jolin, Anas Younes, Keenan Fenton, Stephen M. Ansell, Joseph M. Connors, Andrew Grigg, Won Seog Kim, Ashish Gautam, Kerry J. Savage, Rachael Liu, Monika Długosz-Danecka |
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| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Neutropenia Dacarbazine Vinblastine Bleomycin chemistry.chemical_compound Older patients Internal medicine Antineoplastic Combined Chemotherapy Protocols polycyclic compounds medicine Humans Doxorubicin Brentuximab vedotin Aged Neoplasm Staging Manchester Cancer Research Centre business.industry ResearchInstitutes_Networks_Beacons/mcrc Peripheral Nervous System Diseases Cancer Hematology medicine.disease Hodgkin Disease ABVD chemistry business medicine.drug |
| Zdroj: | Evens, A M, Connors, J M, Younes, A, Ansell, S M, Kim, W S, Radford, J, Feldman, T, Tuscano, J, Savage, K J, Oki, Y, Grigg, A, Pocock, C, Dlugosz-Danecka, M, Fenton, K, Forero-Torres, A, Liu, R, Jolin, H, Gautam, A & Gallamini, A 2021, ' Older patients (aged ≥60 years) with previously untreated advanced-stage classical Hodgkin lymphoma : a detailed analysis from the phase III ECHELON-1 study ', Haematologica . https://doi.org/10.3324/haematol.2021.278438 |
| ISSN: | 1592-8721 0390-6078 |
| Popis: | Effective and tolerable treatments are needed for older patients with classical Hodgkin lymphoma. We report results for older patients with classical Hodgkin lymphoma treated in the large phase III ECHELON-1 study of frontline brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine (A+AVD) versus doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD). Modified progression-free survival per independent review facility for older versus younger patients (aged ≥60 vs. |
| Databáze: | OpenAIRE |
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