A newborn with respiratory distress and hydrocephalus caused by a giant mature teratoma

Autor: Hacı Ahmet Demir, Sevim Ünal, Ayper Kaçar, Leyla Bilgin, Belgin Akcan
Rok vydání: 2011
Předmět:
Zdroj: Child's Nervous System. 28:633-636
ISSN: 1433-0350
0256-7040
DOI: 10.1007/s00381-011-1612-9
Popis: Teratomas, derived from pluripotent cells, are the most common neonatal tumors and are mainly located in the sacrococcygeal region or mediastinum [3]. They commonly present as large and deforming monstrous tumors with an incidence of 1 in 20,000 to 40,000 newborns. The lesion is usually life threatening due to airway obstruction, and their aetiology is uncertain. The head and neck localization comprises 2% to 9% of all teratomas. Most are very large and complex lesions containing solid and cystic areas. These lesions contain all three germ layers and may be composed of mature or immature elements. In the neonate, the presence of immature elements does not correlate with malignant potential, and most of these teratomas are benign [1, 3, 6, 12, 13]. We present a newborn with a giant head and neck mass visualised postnatally by cranial magnetic resonance imaging (MRI). The histopathological diagnosis made on the basis of excisional biopsy was mature teratoma. Total surgical resection was not possible due to massive invasion of airways and central nervous system (CNS) by the tumor. The clinical and radiological characteristics, as well as mortality, in this case of a teratoma are discussed.
Databáze: OpenAIRE
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