Radiotherapy in the multimodal treatment of extrarenal extracranial malignant rhabdoid tumors
| Autor: | Paul A. Meyers, Michael P. LaQuaglia, Suzanne L. Wolden, Dev R. Puri, Dennis H. Kraus, Leonard H. Wexler |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Chemotherapy business.industry medicine.medical_treatment Multimodality Treatment Optimal treatment Rhabdoid tumors Infant Hematology Disease Combined Modality Therapy Radiation therapy Oncology Head and Neck Neoplasms Pediatrics Perinatology and Child Health medicine Diseases in Twins Multimodal treatment Humans Female Radiology business Child Rhabdoid Tumor |
| Zdroj: | Pediatric bloodcancer. 50(1) |
| ISSN: | 1545-5017 |
| Popis: | Extrarenal extracranial malignant rhabdoid tumors (MRT) are extremely rare and typically lethal. No consensus exists on an optimal treatment approach, and, in particular, the role of radiation therapy (RT) is poorly defined. We report on three children who underwent multimodality treatment including surgery, chemotherapy (CMT), and RT. Two of these patients are alive and without evidence of disease 6(1/2) and 7 years after diagnosis and one has expired. Our limited experience suggests that RT in the setting of CMT and surgery has the potential to prolong survival with acceptable toxicity, but outcomes are inconsistent and further study is necessary. |
| Databáze: | OpenAIRE |
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