Visualization of tumor vascularity in a rabbit VX2 carcinoma by Doppler flow mapping
| Autor: | R A Zlotecki, Jonathan M. Rubin, Paul L. Carson, W D Ensminger |
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| Rok vydání: | 1987 |
| Předmět: |
Pathology
medicine.medical_specialty Epinephrine symbols.namesake Doppler flow Medicine Animals Radiology Nuclear Medicine and imaging Vx2 carcinoma Ultrasonography Radiological and Ultrasound Technology Fourier Analysis business.industry Soft tissue Videotape Recording Rabbit (nuclear engineering) Neoplasms Experimental Visualization Regional Blood Flow Tumor vascularity symbols Ultrasonic sensor Female Rabbits business Doppler effect Neoplasm Transplantation Biomedical engineering |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 6(3) |
| ISSN: | 0278-4297 |
| Popis: | Using an ultrasonic dynamic flow imager that displays both soft tissues and color-coded flow in the same two-dimensional slice, we were able to display neovascularity in a rabbit VX2 carcinoma. Intravenous infusion of epinephrine altered the flow dynamics in two arteries, one within the tumor and one at the periphery. Further, we were also able to visualize areas of multidirectional flow presumably due to complex arterial patterns and arteriovenous shunts. It is concluded that the color-coded Doppler instrument may overcome some of the methodological problems associated with tumor diagnosis via flow characteristics in the human breast. The literature indicates that the vascular response to the vasoactive drugs or thermal stress may increase differentiation of malignant breast lesions. This experiment suggests that Doppler images and measurements may be made efficiently with color-coded Doppler images, particularly with the addition of more quantitative features to the imager. |
| Databáze: | OpenAIRE |
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