Promoter polymorphism of second tryptophan hydroxylase isoform (TPH2) in schizophrenia and suicidality
| Autor: | James L. Kennedy, Takahiro Shinkai, Gregory W.H. Wong, Daphne Voineskos, John Strauss, Vincenzo De Luca, Claudia Rothe |
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| Rok vydání: | 2004 |
| Předmět: |
Gene isoform
Adult Genetic Markers Male Psychosis Suicide Attempted Tryptophan Hydroxylase Polymorphism (computer science) medicine Humans Protein Isoforms Allele Biological Psychiatry Aged Genetics Chi-Square Distribution Polymorphism Genetic TPH2 Chromosomes Human Pair 11 Incidence Haplotype Tryptophan hydroxylase Middle Aged medicine.disease Psychiatry and Mental health Haplotypes Genetic marker Schizophrenia Female Psychology |
| Zdroj: | Psychiatry research. 134(2) |
| ISSN: | 0165-1781 |
| Popis: | Allele and haplotype frequencies of a promoter polymorphism in the gene encoding tryptophan hydroxylase (TPH2) did not differ in 83 suicidal schizophrenic patients compared with 170 non-suicidal schizophrenic patients. These findings suggest that these 5' marker haplotypes in the TPH2 gene do not influence suicidal behavior in schizophrenia. |
| Databáze: | OpenAIRE |
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